by Brooks | Jul 21, 2025 | Dictionary
Pharmacodynamics (PD) is the study of how a drug affects an organism physiologically and biochemically, such as the relationships between the measured drug concentration and its efficacy and adverse effects (Kielbasa and Helton, 2019)....
by Brooks | Jul 21, 2025 | Dictionary
A tool that uses a person’s genetic information to help determine which medications and doses are likely to work best for them (Kabbani et al., 2023). https://www.genome.gov/about-genomics/educational-resources/fact-sheets/pharmacogenomics Learn More Genomic...
by Brooks | Jul 21, 2025 | Dictionary
also known as massively parallel sequencing; technologies for sequencing DNA that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method of Sanger sequencing)....
by Brooks | Jul 21, 2025 | Dictionary
A haplotype is a set of DNA variations (polymorphisms, like SNPs and indels) on a chromosome that tend to be inherited together, often referred to as linked polymorphisms. https://www.genome.gov/genetics-glossary/haplotype UGenome.IO Making genomic medicine personal...
by Brooks | Jul 21, 2025 | Dictionary
all the effects of a drug on an individual in relation to effectiveness, side effects, and adverse reactions https://www.sciencedirect.com/topics/immunology-and-microbiology/drug-response UGenome.IO Making genomic medicine personal and accessible for everyone Learn...
by Brooks | Jul 21, 2025 | Dictionary
Drug metabolism or drug biotransformation is the process by which xenobiotics are enzymatically modified to make them more readily excretable and eliminate pharmacological activity (Sane & Sinz, 2017). https://www.ncbi.nlm.nih.gov/books/NBK442023 UGenome.IO Making...
