UGenome Blog

Polymorphisms

Polymorphism, as related to genomics, refers to the presence of two or more variant forms of a specific DNA sequence that can occur among different individuals or populations.  https://www.genome.gov/genetics-glossary/Polymorphism UGenome.IOMaking genomic medicine...

Somatic Variations

Somatic variation refers to DNA changes (mutations) that happen in body cells (somatic cells) after conception, not in reproductive cells (sperm/egg), meaning they aren't inherited by offspring but can affect the individual, often causing sporadic cancers,...

System Biology

System biology is an approach in biomedical research to understanding the larger picture—be it at the level of the organism, tissue, or cell—by putting its pieces together. It’s in stark contrast to decades of reductionist biology, which involves taking the pieces...

HaplotypeCaller

The HaplotypeCaller is capable of calling SNPs and indels simultaneously via local de-novo...

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Metagenomics

Metagenomics is the study of the structure and function of entire nucleotide sequences isolated...

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Nutrigenetics

The heterogeneous response of gene variants to nutrients, dietary components and developing...

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